Мы хотели бы показать здесь описание, но сайт, который вы просматриваете, этого не позволяет.In one particular embodiment, LAG-3 positive or LAG-3 expression positive tumor means that at least about 1%, or in the range of 1- 5% of the total number of tumor-infiltrating inflammatory cells (e.g., T cells, CD8+ T cells, CD4+ T cells, FOXP3+ cells) express LAG-3 on the cell surface.2. A valvular conduit composed of a closed passageway having recesses in its or passageway with rigid interior walls formed with a series of recesses or pockets with surfaces that reverse a fluid tending to flow in one direction therein and thereby check or prevent flow of the fluid in thatdirection. 'l.Online patent tools. Locate online patent services and information. Patent Center. Single interface replacement for EFS-Web, Private PAIR and Public PAIR. Electronic Business Center; Check application status. Check patent application status with Patent Center. Fees and payment. Pay maintenance fees and learn more about filing … We would like to show you a description here but the site won’t allow us. U.S. Patent No. 7,326,708discloses crystalline sitagliptin dihydrogenphosphate monohydrate and a process for its preparation. It also discloses that the crystalline dihydrogenphosphate salt of the present invention exhibits pharmaceutic advantages over the free base and the previously disclosed hydrochloride salt. Patents. We currently index full-text documents from the following patent offices: You can see the real-time number of documents that are included from each patent office by clicking on "around the world" on patents.google.com . These totals include all patents and published applications in our index, but we cannot guarantee complete coverage. Delivery: As used herein, “delivery” refers to the act or manner of delivering a compound, substance, entity, moiety, cargo or payload. Delivery Agent: As used herein, “delivery agent” refers to any substance which facilitates, at least in part, the in vivo delivery of a nucleic acid molecule to targeted cells.OF DAY'lUX, OlllU. ' FLYING-MACHINE. fipeciflcatiqn ofLettera Patent. .Eatented May 22, 1906. Application fi1 ad'Mai-ch 28,190- Serial No. 149.220; 1 and WILBUR Wmen'r, citizens of-the United n of Montgomery, and State of .0. States, residing in the city of Da ton, county no, have invented as eciiicat'ion; ur invention rlatesto that class …Wikipedia entry for Google Patents.Google Patents is a search engine from Google that indexes patents and patent applications from the United States Patent and Trademark Office.Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 1996-12-13 Filing date 2002-04-24 Publication date 2003-07-01 ... 2002-09-05 Publication of US20020123775A1 publication Critical patent/US20020123775A1/en 2003-07-01 Application granted granted Critical5. Nike’s golf glasses: Up your game with a futuristic display. Source: Wojciech Kulicki/Flickr. Golf is set to get a 21st Century upgrade, thanks to Nike’s acquisition of a patent for a ...Мы хотели бы показать здесь описание, но сайт, который вы просматриваете, этого не позволяет.Tips on searching Google patents, including operators, using classifications and more. Cooperative Patent Classification. Harmonized system used by USPTO and …About Google Patents. Coverage. Next: Searching. Google Patents includes over 120 million patent publications from 100+ patent offices around the world, as well as many …Online patent tools. Locate online patent services and information. Patent Center. Single interface replacement for EFS-Web, Private PAIR and Public PAIR. Electronic Business Center; Check application status. Check patent application status with Patent Center. Fees and payment. Pay maintenance fees and learn more about filing …2005-08-30. Method and apparatus for personalized conference and hands-free telephony using audio beaming. US11082763B2 ( en ) 2021-08-03. Handheld acoustic hailing and disruption systems and methods. US20170148466A1 ( en ) 2017-05-25. Method and system for reducing background sounds in a noisy environment.UNrrn TATES PATENT OFFICE. ALEXANDER GLEASON, OF BUFFALO, NEIV YORK, ASSIGNOR TO THE BUF FALO ELEOTROTYPE AND ENGRAVING COMPANY, OF SAME PLACE. TIME-CHART. SPECIFICATION forming part of Letters Patent No. 497,917, dated May 23, 1893. Application filed August 15, 1892.The present disclosure relates to the field of vaccines and binding molecules, as well as preparations and methods of their use in the treatment and/or prevention of disease. Described are vaccines and binding molecules, compositions containing the same, and uses thereof for treating or preventing coronavirus infections, in particular, β …2005-08-30. Method and apparatus for personalized conference and hands-free telephony using audio beaming. US11082763B2 ( en ) 2021-08-03. Handheld acoustic hailing and disruption systems and methods. US20170148466A1 ( en ) 2017-05-25. Method and system for reducing background sounds in a noisy environment.Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 1953-04-10 Filing date 1954-04-09 Publication date 1957-10-15 ... In a Japanese patent application (application No. 1676/50, publicized on June 5, 1950) a process was described according to which a certain strain or ergot (Claviceps ...In one particular embodiment, LAG-3 positive or LAG-3 expression positive tumor means that at least about 1%, or in the range of 1- 5% of the total number of tumor-infiltrating inflammatory cells (e.g., T cells, CD8+ T cells, CD4+ T cells, FOXP3+ cells) express LAG-3 on the cell surface.Publication Publication Date Title. US6468525B1 2002-10-22 Probiotic formulation. TWI574633B 2017-03-21 Compositions comprising probiotic and prebiotic components and mineral salts, with lactoferrin. US8404228B2 2013-03-26 Food containing a probiotic and an isolated β-glucan and methods of use thereof.Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2014-05-28 Filing date 2015-05-27 Publication date 2016-07-19 2014-10-02 Priority claimed from US14/505,478 external-priority patent/US9537811B2/en 2015-05-27 Priority to US14/723,400 priority Critical patent/US9396354B1/enMar 19, 2019 · The Basics of Google Patent Search. First, there’s no universal “best” way to perform a Google patent search. That said, this article will outline how we approach patent searches—which happens to be the best way to start. Note the checkbox beneath the search menu. Check that if you want to include non-patent literature in your search. A method for inducing cats to exercise consists of directing a beam of invisible light produced by a hand-held laser apparatus onto the floor or wall or other opaque surface in the vicinity of the cat, then moving the laser so as to cause the bright pattern of light to move in an irregular way fascinating to cats, and to any other animal with a ...U.S. Provisional Patent Application No. 61/709,303 filed Oct. 3, 2012, entitled Modified Nucleoside, Nucleotide and Nucleic Acid Compositions, U.S. Provisional Patent Application No. exogenous unmodified nucleic acid …Tips on searching Google patents, including operators, using classifications and more. Cooperative Patent Classification. Harmonized system used by USPTO and …US8366547B2 * 2010-12-06 2013-02-05 Ignite Game Technologies, Inc. Racing car wheel and controls for use in a multimedia interactive environment. US8641525B2 2011-06-17 2014-02-04 Ironburg Inventions Ltd. Controller for video game console.U.S. Patent No. 7,326,708discloses crystalline sitagliptin dihydrogenphosphate monohydrate and a process for its preparation. It also discloses that the crystalline dihydrogenphosphate salt of the present invention exhibits pharmaceutic advantages over the free base and the previously disclosed hydrochloride salt.The invention belongs to the field of nano materials and biomedicine, and relates to a vaccine, in particular to development of 2019-nCoV coronavirus nuclear recombinant nano vaccine. The invention also comprises a preparation method of the vaccine and application of the vaccine in animal experiments. The new corona vaccine contains graphene oxide, …This patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results.Мы хотели бы показать здесь описание, но сайт, который вы просматриваете, этого не позволяет.A method for inducing cats to exercise consists of directing a beam of invisible light produced by a hand-held laser apparatus onto the floor or wall or other opaque surface in the vicinity of the cat, then moving the laser so as to cause the bright pattern of light to move in an irregular way fascinating to cats, and to any other animal with a ...USPTO’s new Diversity Information Platform: Advancing innovation through data-driven action. The unique online platform is free and available to anyone with an internet connection. Home page of the United States Patent and …This invention relates to a method for the reduction of global warming resulting from the greenhouse effect, and in particular to a method which involves the seeding of the earth's stratosphere with Welsbach-like materials. Global warming has been a great concern of many environmental scientists. Scientists believe that the greenhouse effect is ...a further embodiment of the invention is a process for stabilizing ascorbic acid for storage, the process comprising combining 0.2% to 0.5% of a cinnamic acid derivative, such as p-coumaric acid, ferulic acid, caffeic acid, sinapinic acid, a derivative thereof, or a combination thereof; 10% to 60% of a solvent comprising a glycol ether and an alkanediol; and water; …A magnesium-counter ion composition provided herein may be useful for administration to a subject presenting magnesium deficiency, mild cognitive impairment, Alzheimer's disease, attention deficit hyperactivity disorder, ALS, Parkinson's disease, diabetes, migraine, anxiety disorder, mood disorder, and/or hypertension.This invention is a training system that enables a human being to acquire sufficient hyperspace energy in order to pull the body out of dimension so that the person can walk through solid objects such as wooden doors. A human being is a hyperspace energy being living in a physical container or body that is comprised of 67% water.Opens Google Patents for a selected patent identifier. This solution allows you to quickly open Google Patents for a selected patent identifier. Select a patent identifier in text, then open the context menu and select "Open Google Patents" from the menu. You can normally open the context menu by right-clicking. FIELD OF THE INVENTION. The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease. BACKGROUND TO THE INVENTION. Aug 1, 2023 · Google Patents. Google Inc. operates the Google search engine and the platform that delivers targeted ads to its users. The company also offers the GMail e-mail service, the Chrome web browser, the Google Play digital content store, as well as the Android mobile operating system. SUMMARY OF THE INVENTION [0007] In one aspect of the invention, compounds are provided that inhibit KRas G12D activity. In certain embodiments, the compounds are represented by Formula (I): Formula (I) [0008] or a pharmaceutically acceptable salt thereof: [0009] wherein: [00010] R 1 is hydrogen, hydroxy, halogen, C1 – C3 alkyl, C1 - C3 ... Oct 1, 2021 · A messenger ribonucleic acid (mRNA) comprising an open reading frame (ORF) that encodes at least two domains of a SARS-CoV-2 Spike protein, and less than the full length spike protein. 2. The mRNA of claim 1, wherein one of the two domains is an N-terminal domain (NTD) of a SARS-CoV-2 Spike protein. 3. Patents laws. Search for a patent. Apply for a patent. Forms and fees. HK IP Journal. Patents Examination Guidelines. Managing your patent. FAQs. Patent system since December 2019 and New initiatives.JP2016523981A5 - - Google Patents. Other languages. English. Worldwide applications. 2014 PT CA WO EP BR RS JP HU CN SI US ES AU EP PL DK LT 2016 IL 2018 US US 2020 US 2021 CY HR 2023 US. Application JP2016525813A events. 2013-08-13. Priority claimed from US13/966,229. 2014-07-11.Apr 25, 2024 · This patent search tool allows you not only to search the PCT database of about 2 million International Applications but also the worldwide patent collections. This search facility features: flexible search syntax; automatic word stemming and relevance ranking; as well as graphical results. Patent Opportunity Submission Portal – Google. Google receives many unsolicited patent inquiries. In order to help us route and evaluate your request, please use the following …About Google Patents. Coverage. Next: Searching. Google Patents includes over 120 million patent publications from 100+ patent offices around the world, as well as many …US8366547B2 * 2010-12-06 2013-02-05 Ignite Game Technologies, Inc. Racing car wheel and controls for use in a multimedia interactive environment. US8641525B2 2011-06-17 2014-02-04 Ironburg Inventions Ltd. Controller for video game console.Google has long history of making patent data universally accessible and useful, starting more than 10 years ago by scanning old US patents into Google Patents. Today, Google is...Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2014-05-28 Filing date 2015-05-27 Publication date 2016-07-19 2014-10-02 Priority claimed from US14/505,478 external-priority patent/US9537811B2/en 2015-05-27 Priority to US14/723,400 priority Critical patent/US9396354B1/enPatent Opportunity Submission Portal – Google. Google receives many unsolicited patent inquiries. In order to help us route and evaluate your request, please use the following …Oct 1, 2021 · A messenger ribonucleic acid (mRNA) comprising an open reading frame (ORF) that encodes at least two domains of a SARS-CoV-2 Spike protein, and less than the full length spike protein. 2. The mRNA of claim 1, wherein one of the two domains is an N-terminal domain (NTD) of a SARS-CoV-2 Spike protein. 3. Publication Publication Date Title. US4750A 1846-09-10 Improvement in sewing-machines. US171558A 1875-12-28 Improvement in sewing-machines. US28785A 1860-06-19 Improvement in sewing-machines. US25913A 1859-10-25 Improvement in sewing-machines. US34748A 1862-03-25 Improvement in sewing-machines.2. A coil composed'of contiguous or adjacent insulated conductors electrically con; nected in seriesand having a potential ditference of such value as to give to the coil as a whole, a capacity sufficient to neutralize its self-induction, as set forth. NIKOLA TESLA. ` …The invention belongs to the field of nano materials and biomedicine, and relates to a vaccine, in particular to development of 2019-nCoV coronavirus nuclear recombinant nano vaccine. The invention also comprises a preparation method of the vaccine and application of the vaccine in animal experiments. The new corona vaccine contains graphene oxide, … We would like to show you a description here but the site won’t allow us. May 26, 2020 · Google Patents is a search platform with 120+ million patent dataset covering in 100+ jurisdiction that makes it one of the best available patent databases. April 24, 2024 +1-202-455-5058 [email protected] The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell …USPTO’s new Diversity Information Platform: Advancing innovation through data-driven action. The unique online platform is free and available to anyone with an internet connection. Home page of the United States Patent and …US8983682B1 * 2012-12-28 2015-03-17 Google Inc. Unlocking mobile-device and/or unmanned aerial vehicle capability in an emergency situation. US9051043B1 * 2012-12-28 2015-06-09 Google Inc. Providing emergency medical services using unmanned aerial vehicles. USD741751S1 * 2014-12-11 2015-10-27 SenseFly Ltd. Drone.Мы хотели бы показать здесь описание, но сайт, который вы просматриваете, этого не позволяет.The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides …38,268. 2022. 35,315. 1,173. 12,077. 13,699. 62,264. In 2022, China was granted more patents than every other country combined. While this suggests that the …6. The controller of claim 1, wherein the input device is a button, the button being configured to activate a sharing interface for sharing recorded gameplay to a social graph of a user. 7. The controller of claim 6, wherein sharing recorded gameplay includes sharing one or more of an image or a video clip.Patent Citations (84) Publication number Priority date Publication date Assignee Title. Family To Family Citations. 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations. 1986-03-27 1993-07-06 Medical Research Council Recombinant altered antibodies and methods of making altered antibodies.UNITED STATES PATENT OFFICE. NIKOLA TESLA, OF NEW YORK, N. Y., ASSIGNOB O F ONE-HALF TO CHARLES F. PECK, OF ENGLEWOOD, NEW JERSEY. ELECTRO-MAGN-ETIC MOTOR. SPECIFICATION forming part of Letters Patent No. 381.968, dated May-1, 1888. Application filed October 12. 1857.Publication Publication Date Title. US6468525B1 2002-10-22 Probiotic formulation. TWI574633B 2017-03-21 Compositions comprising probiotic and prebiotic components and mineral salts, with lactoferrin. US8404228B2 2013-03-26 Food containing a probiotic and an isolated β-glucan and methods of use thereof.Jun 4, 2021 · Formula to generate search URLs. This file: Google spreadsheet 10. Filter search results. Lastly, on the search result page, you can apply different filters on the “Patent Office”, the ... On August 13, 2010, Oracle sued Google for copyright and patent infringement in the District Court for the Northern District of California. Oracle asserted Google was aware that they had developed Android without a Java license and copied its APIs, and that Google therefore infringed Oracle's copyright.May 26, 2020 · Google Patents is a search platform with 120+ million patent dataset covering in 100+ jurisdiction that makes it one of the best available patent databases. April 24, 2024 +1-202-455-5058 [email protected] A magnesium-counter ion composition provided herein may be useful for administration to a subject presenting magnesium deficiency, mild cognitive impairment, Alzheimer's disease, attention deficit hyperactivity disorder, ALS, Parkinson's disease, diabetes, migraine, anxiety disorder, mood disorder, and/or hypertension. A method is provided for acquiring and transmitting biometric data (e.g., vital signs) of a user, where the data is analyzed to determine whether the user is suffering from a viral infection, such as COVID-19. The method includes using a pulse oximeter to acquire at least pulse and blood oxygen saturation percentage, which is transmitted ... Publication Publication Date Title. CN105069156A 2015-11-18 Patent searching system. CN105138661B 2018-10-30 A kind of network security daily record k-means cluster analysis systems and method based on Hadoop. DE602005007722D1 2008-08-07 MULTIPLE ACCESS POINTS.UNITED STATES PATENT OFFICE. NIKOLA TESLA, OF NEW YORK, N. Y., ASSIGNOB O F ONE-HALF TO CHARLES F. PECK, OF ENGLEWOOD, NEW JERSEY. ELECTRO-MAGN-ETIC MOTOR. SPECIFICATION forming part of Letters Patent No. 381.968, dated May-1, 1888. Application filed October 12. 1857.What is Google Patents. Google Patents is Google's own patent search tool. It draws on patents from more than 100 of the biggest patent offices from around the …We would like to show you a description here but the site won’t allow us.Includes an Advanced Search and Prior Art Finder. Take greater control of your Google Patents search, utilising search boxes for specific keyword or numeric …This invention is a training system that enables a human being to acquire sufficient hyperspace energy in order to pull the body out of dimension so that the person can walk through solid objects such as wooden doors. A human being is a hyperspace energy being living in a physical container or body that is comprised of 67% water.Google patents database is built using patents from 17 patent offices* around the world. The database contains over 87 million patent publications including. Search Techniques. You can directly type text in the search bar. The search engine splits search strings and searches individual keywords in the search string.Google's Patent Opportunity Submission Portal. Google will consider licensing offers for granted patents submitted through this portal.Abstract. The invention provides for application of Salicylic Acid, in proportion and concentration depending upon the size of cancer, onto or into a cancerous area in the body, in order to reduce and remove the cancer. Upon application, Salicylic Acid will destroy all the extra cells in the body that form cancer and rid the body of cancer.The base plate, constituting the fundamental element of the brick, is generally designated by 1, the projections extending from one face of the base plate are hereinafter referred to as the primary projections 21, and the projections at the other face are referred to as the sec- 3,005,282 Patented Oct. 24, 1961 2 ondary projections 22.3-D diamond printing using a pre-ceramic polymer with a nanoparticle filler. JP2015171780A ( en ) *. 2014-03-12. 2015-10-01. セイコーエプソン株式会社. Method for manufacturing three-dimensional molded article, apparatus for manufacturing three-dimensional molded article, and three-dimensional molded article.Publication Publication Date Title. US4750A 1846-09-10 Improvement in sewing-machines. US171558A 1875-12-28 Improvement in sewing-machines. US28785A 1860-06-19 Improvement in sewing-machines. US25913A 1859-10-25 Improvement in sewing-machines. US34748A 1862-03-25 Improvement in sewing-machines.Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2014-05-28 Filing date 2015-05-27 Publication date 2016-07-19 2014-10-02 Priority claimed from US14/505,478 external-priority patent/US9537811B2/en 2015-05-27 Priority to US14/723,400 priority Critical patent/US9396354B1/en We would like to show you a description here but the site won’t allow us.
Data provided by IFI CLAIMS Patent Services. A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a therapeutically effective amount of famotidine is administered three times per day.. Prmoviws
Includes an Advanced Search and Prior Art Finder. Take greater control of your Google Patents search, utilising search boxes for specific keyword or numeric …3-D diamond printing using a pre-ceramic polymer with a nanoparticle filler. JP2015171780A ( en ) *. 2014-03-12. 2015-10-01. セイコーエプソン株式会社. Method for manufacturing three-dimensional molded article, apparatus for manufacturing three-dimensional molded article, and three-dimensional molded article.2005-08-30. Method and apparatus for personalized conference and hands-free telephony using audio beaming. US11082763B2 ( en ) 2021-08-03. Handheld acoustic hailing and disruption systems and methods. US20170148466A1 ( en ) 2017-05-25. Method and system for reducing background sounds in a noisy environment. Search within the title, abstract, claims, or full patent document: You can restrict your search to a specific field using field names.. Use TI= to search in the title, AB= for the abstract, CL ... Using PATENTSCOPE you can search 116.1 million patent documents including 4.8 million published international patent applications (PCT). Detailed coverage …US20200054559A1. The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides vaccine nanocarriers capable of stimulating an immune response in T cells and/or in B cells, in some embodiments, comprising at least one immunomodulatory agent, and optionally …First worldwide family litigation filed. 2013-12-16. Priority to US14/106,988. 2013-12-16. Application filed by Moderna Therapeutics Inc. 2014-04-17. Publication of US20140107189A1. 2016-04-05. Publication of US9301993B2. Google Patents is a search engine from Google that indexes patents and patent applications from the United States Patent and Trademark Office, European Patent Office, and World Intellectual Property Organization. These documents include the entire collection of granted patents and published patent applications from each database. Publication Publication Date Title. US6468525B1 2002-10-22 Probiotic formulation. TWI574633B 2017-03-21 Compositions comprising probiotic and prebiotic components and mineral salts, with lactoferrin. US8404228B2 2013-03-26 Food containing a probiotic and an isolated β-glucan and methods of use thereof.Find details of patents to: check if a similar patent to your invention already exists; track the progress of a published patent application; see if patents are available to license;...1. Start with a simple keyword search. Go to patents.google.com and enter the keywords in the search bar. Example query: oral care. This will returns patents …The present disclosure relates to the field of vaccines and binding molecules, as well as preparations and methods of their use in the treatment and/or prevention of disease. Described are vaccines and binding molecules, compositions containing the same, and uses thereof for treating or preventing coronavirus infections, in particular, β …Aug 1, 2023 · Google Patents. Google Inc. operates the Google search engine and the platform that delivers targeted ads to its users. The company also offers the GMail e-mail service, the Chrome web browser, the Google Play digital content store, as well as the Android mobile operating system. Global Dossier. Patent Application Information Retrieval (PAIR) Public Search Facility. Patent and Trademark Resource Centers (PTRCs) Patent Official …Oct 1, 2021 · A messenger ribonucleic acid (mRNA) comprising an open reading frame (ORF) that encodes at least two domains of a SARS-CoV-2 Spike protein, and less than the full length spike protein. 2. The mRNA of claim 1, wherein one of the two domains is an N-terminal domain (NTD) of a SARS-CoV-2 Spike protein. 3. JP2016523981A5 - - Google Patents. Other languages. English. Worldwide applications. 2014 PT CA WO EP BR RS JP HU CN SI US ES AU EP PL DK LT 2016 IL 2018 US US 2020 US 2021 CY HR 2023 US. Application JP2016525813A events. 2013-08-13. Priority claimed from US13/966,229. 2014-07-11.Data provided by IFI CLAIMS Patent Services. A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a therapeutically effective amount of famotidine is administered three times per day..